Which locations do I need for my index to include e-mail messages and attachments, Address Book, iCal events, Safari Bookmarks and other metadata ?

We recommend adding at least the following folders to the data to be indexed:

CTM PowerMail:/Users/MyUserName/Mail/PowerMail\ Files

Apple Mail:/Users/MyUserName/Library/Mail and/Users/MyUserName/Library/Mail Downloads

Apple Address Book:/Users/MyUserName/Library/Application Support/AddressBook/Metadata

iCal:/Users/MyUserName/Library/Calendars

OmniFocus:/Users/MyUserName/Library/Caches/Metadata/com.omnigroup.OmniFocus

Safari:/Users/MyUserName/Library/Caches/Metadata/Safari